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This article is part of the supplement: Proceedings of the 11th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI): Basic, Epidemiologic, and Clinical Research .

Open AccessOral presentation

Epidemiology of non-keratinocytic skin cancers among persons with AIDS in the United States

E Lanoy1,2, GM Dores1,3, MM Madeleine4, JR Toro1, JF Fraumeni1 and EA Engels1

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville Maryland, USA

INSERM, U720, Paris, France

Medical Service, Department of Veterans Affairs Medical Center, Oklahoma City, Oklahoma, USA

Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

corresponding author email

from 11th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI): Basic, Epidemiologic, and Clinical Research
Bethesda, MD, USA. 6–7 October 2008

Infectious Agents and Cancer 2009, 4(Suppl 2):O10doi:10.1186/1750-9378-4-S2-O10

Published: 17 June 2009

First paragraph (this article has no abstract)

Immunosuppression may increase the risk for some skin cancers. Solid organ transplant recipients have an elevated risk for melanoma and, to a greater extent, squamous and basal cell carcinomas (two skin cancers derived from keratinocytes). The frequency and patterns of occurrence of skin cancers in HIV-infected persons have not been well documented. Ultraviolet radiation is an established risk factor for the various types of skin cancer. In the present study, we used linked AIDS and cancer registry data to examine skin cancer epidemiology among persons with AIDS. Cancer registries in the United States do not collect information on the occurrence of the two most common types of skin cancer, squamous cell and basal cell skin carcinomas, so these outcomes could not be included. Thus, our study focuses on the occurrence of melanoma, Merkel cell carcinoma, and appendageal carcinomas among persons with AIDS.


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