Infectious Agents and Cancer

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This article is part of the supplement: Proceedings of the 11th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI): Basic, Epidemiologic, and Clinical Research

Open Access Oral presentation

Immunodeficiency, HIV RNA plasma viral load and risk of AIDS-defining and non-AIDS-defining neoplasia, ANRS CO3 Aquitaine Cohort (1998–2006)

M Bruyand1,2*, R Thiebaut3,1,2, F Dabis3,1,2, S Lawson-Ayayi1,2, P Joly3, AJ Sasco3,1, P Mercie3,4,1,2, JL Pellegrin3,4,2, S Geffard1, D Neau3,4,2, P Morlat3,4,1,2, G Chene3,1,2, F Bonnet3,4,1,2 and the Goupe D'Epidemiologie Clinique Du Sida En Aquitaine (GECSA)3,1,2

  • * Corresponding author: M Bruyand

Author Affiliations

1 INSERM U897, Bordeaux, France

2 CHU de Bordeaux, Coordination Régionale de la lutte contre l'infection due au VIH (COREVIH), Bordeaux, France

3 Université Victor Segalen Bordeaux 2, Bordeaux, France

4 Services de Médecine Interne et Maladies Infectieuses, CHU de Bordeaux, Bordeaux, France

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Infectious Agents and Cancer 2009, 4(Suppl 2):O3 doi:10.1186/1750-9378-4-S2-O3

Published: 17 June 2009

First paragraph (this article has no abstract)

The risk of neoplasis is increased in HIV-infected subjects. Beside traditional determinants of cancer occurrence, a specific role of HIV-related immunosuppression is strongly suspected and a more complex relationship between HIV and antiretroviral therapy (ART) cannot be excluded. Our objective was to disentangle the relationship between some frequently diagnosed cancers in HIV-infected patients and immunosuppression, HIV and ART exposure.