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This article is part of the supplement: Proceedings of the 11th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI): Basic, Epidemiologic, and Clinical Research .

Open AccessPoster presentation

Immunophenotypic analysis of AIDS-related diffuse large B-cell lymphoma and clinical implications in patients from AIDS malignancies consortium clinical trials 010 and 034

A Chadburn1, A Chiu1, Y Lee2, X Chen1, E Hyjek1, A Banhmam3, A Noy4, A Kaplan5, J Sparano6, K Bhatia7, E Cesarman1 and the Aids Malignancy Consortium

Weill Cornell Medical College, New York, New York, USA

University of Alabama at Birmingham, Birmingham, Alabama, USA

Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Headington, Oxford, UK

Memorial Sloan Kettering Cancer Center, New York, New York, USA

University of California-San Francisco, San Francisco, California, USA

Albert Einstein Comprehensive Cancer Center, New York, New York, USA

National Cancer Institute, National Institutes of Health Washington, D.C., USA

corresponding author email

from 11th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI): Basic, Epidemiologic, and Clinical Research
Bethesda, MD, USA. 6–7 October 2008

Infectious Agents and Cancer 2009, 4(Suppl 2):P14doi:10.1186/1750-9378-4-S2-P14

Published: 17 June 2009

First paragraph (this article has no abstract)

Diffuse large B cell lymphoma represents a clinically heterogeneous disease, and several immunohistochemical strategies have been shown to help prognosticate clinical outcome. These include subdivision into germinal center (GC) and non-germinal center (non-GC) subtypes, proliferation index (measured by expression of Ki67), and expression of BCL-2, FOXP1 or Blimp-1/PRDM1. We sought to determine whether immunohistochemical analyses of biopsies from DLBCL patients with HIV infection are similarly relevant for prognostication.


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