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Open Access Research article

Incidence and mortality rates of selected infection-related cancers in Puerto Rico and in the United States

Ana P Ortiz1,2*, Marievelisse Soto-Salgado3, William A Calo3, Guillermo Tortolero-Luna1, Cynthia M Pérez2, Carlos J Romero4, Javier Pérez5, Nayda Figueroa-Vallés1,5 and Erick Suárez2

Author Affiliations

1 Cancer Control and Population Sciences Program, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico

2 Graduate School of Public Health, Department of Biostatistics and Epidemiology, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico

3 Medical Sciences Campus, Puerto Rico Cancer Center, University of Puerto Rico, San Juan, Puerto Rico

4 School of Medicine, Gastroenterology Research Unit, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico

5 Puerto Rico Central Cancer Registry, San Juan, Puerto Rico

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Infectious Agents and Cancer 2010, 5:10 doi:10.1186/1750-9378-5-10

Published: 14 May 2010

Abstract

Background

In 2002, 17.8% of the global cancer burden was attributable to infections. This study assessed the age-standardized incidence and mortality rates of stomach, liver, and cervical cancer in Puerto Rico (PR) for the period 1992-2003 and compared them to those of Hispanics (USH), non-Hispanic Whites (NHW), and non-Hispanic Blacks (NHB) in the United States (US).

Methods

Age-standardized rates [ASR(World)] were calculated based on cancer incidence and mortality data from the PR Cancer Central Registry and SEER, using the direct method and the world population as the standard. Annual percent changes (APC) were calculated using the Poisson regression model from 1992-2003.

Results

The incidence and mortality rates from stomach, liver and cervical cancer were lower in NHW than PR; with the exception of mortality from cervical cancer which was similar in both populations. Meanwhile, the incidence rates of stomach, liver and cervical cancers were similar between NHB and PR; except for NHB women who had a lower incidence rate of liver cancer than women in PR. NHB had a lower mortality from liver cancer than persons in PR, and similar mortality from stomach cancer.

Conclusions

The burden of liver, stomach, and cervical cancer in PR compares to that of USH and NHB and continues to be a public health priority. Public health efforts are necessary to further decrease the burden of cancers associated to infections in these groups, the largest minority population groups in the US. Future studies need to identify factors that may prevent infections with cancer-related agents in these populations. Strategies to increase the use of preventive strategies, such as vaccination and screening, among minority populations should also be developed.