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Open Access Letter to the Editor

Molecular chaperone therapy- the future in cancer

Abdul M Shehzad*, Om Dawani, Shehryar Munir and Syed A Hussain

Author Affiliations

Medical Student, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan

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Infectious Agents and Cancer 2012, 7:20 doi:10.1186/1750-9378-7-20

Published: 13 August 2012

First paragraph (this article has no abstract)

Molecular chaperone or heat shock proteins (HSP) are vital proteins that increase cell survival by allowing it to combat stress caused by injurious stimuli through certain cyto-protective mechanisms [1]. These cyto-protective mechanisms of molecular chaperones, especially HSP 90 [2], have a negative effect designated to favor tumor growth and metastasis among breast cancer, leukemia, pancreatic and ovarian cancer [3,4].